IDO-IN-5(Synonyms: NLG-1489)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

IDO-IN-5 (Synonyms: NLG-1489) 纯度: 95.16%

IDO-IN-5 (NLG-1489) 是一种哚胺-2,3-双加氧酶 (IDO) 抑制剂,IC50 值为 1-10 μM,详细信息请参考专利文献 WO2012142237A1 中的化合物 1489。

IDO-IN-5(Synonyms: NLG-1489)

IDO-IN-5 Chemical Structure

CAS No. : 1402837-79-9

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生物活性

IDO-IN-5 (NLG-1489) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, compound 1489, has an IC50 of 1-10 μM.

IC50 & Target[1]

IDO

1-10 μM (IC50)

体外研究
(In Vitro)

IDO-IN-5 (Compound 1487) is an indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 1-10 μM (this is the concentration of IDO-IN-5 at which inhibits 50% of enzymatic activity using recombinant human IDO)[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

316.37

Formula

C18H21FN2O2

CAS 号

1402837-79-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Mario Mautino, et al. Fused imidazole derivatives useful as ido inhibitors. WO 2012142237 A1.

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