上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Gallic acid hydrate (Synonyms: 没食子酸-水合物; 3,4,5-Trihydroxybenzoic acid hydrate) 纯度: ≥98.0%
Gallic acid (3,4,5-Trihydroxybenzoic acid) hydrate 是一种天然多羟基酚类化合物,具有抑制环氧合酶-2 (COX-2) 的自由基清除作用。Gallic acid hydrate 具有多种活性,如抗菌、抗氧化、抗菌、抗炎和抗肿瘤活性。
Gallic acid hydrate Chemical Structure
CAS No. : 5995-86-8
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
Free Sample (0.1-0.5 mg) | Apply now | ||
10 mM * 1 mL in DMSO | ¥660 | In-stock | |
100 mg | ¥550 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
* Please select Quantity before adding items.
Gallic acid hydrate 相关产品
•相关化合物库:
- Natural Product Library Plus
- Drug Repurposing Compound Library Plus
- FDA-Approved Drug Library Plus
- Bioactive Compound Library Plus
- Apoptosis Compound Library
- Immunology/Inflammation Compound Library
- Metabolism/Protease Compound Library
- NF-κB Signaling Compound Library
- Stem Cell Signaling Compound Library
- Natural Product Library
- FDA-Approved Drug Library
- Anti-Cancer Compound Library
- Human Endogenous Metabolite Compound Library
- Anti-Aging Compound Library
- Drug Repurposing Compound Library
- Antioxidants Compound Library
- Diabetes Related Compound Library
- Oxygen Sensing Compound Library
- Ferroptosis Compound Library
- NMPA-Approved Drug Library
- Medicine Food Homology Compound Library
- Phenols Library
- Pyroptosis Compound Library
- Orally Active Compound Library
- Traditional Chinese Medicine Monomer Library
- FDA Approved & Pharmacopeial Drug Library
- Anti-Pancreatic Cancer Compound Library
- Gut Microbial Metabolite Library
- Microbial Metabolite Library
- Mitochondria-Targeted Compound Library
- Food-Sourced Compound Library
- Anti-Colorectal Cancer Compound Library
生物活性 |
Gallic acid (3,4,5-Trihydroxybenzoic acid) hydrate is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2)[1]. Gallic acid hydrate has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticance activities[2]. |
||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IC50 & Target[1] |
|
||||||||||||||||
体外研究 (In Vitro) |
Gallic acid is an antioxidant which can inhibit both COX-2[1]. After 18 h treatment with Gallic acid, the number of viable neutrophils is dramatically decreased from 40.3% to 27.7%, highly comparable with 26.4% for untreated neutrophils. Gallic acid fails to attenuate isoproterenol-induced myocytolysis[3]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
||||||||||||||||
体内研究 (In Vivo) |
The food intake (2.6±0.08 g/day, p=0.69) and the body weight (2.5±0.69 g, p=0.76) of the Gallic acid group do not differ significantly from those of the control group (food intake; 2.41±0.14 g/day and the body weight; 2.83±0.84 g/day). The blood glucose tolerance in the Gallic acid group is significantly improved after 2 weeks of treatment. The blood glucose tolerance of the Gallic acid group after a treatment period of 2 weeks is also significantly better than that of the control group at 90 and 120 min ( p<0.05). The serum triglyceride concentration in the Gallic acid group (0.67±0.03 mM, p<0.05) is significantly reduced relative to that of the control group (1.08±0.20 mM). The total cholesterol concentration is similar in the control (3.19±0.27 mM) and Gallic acid (3.01±0.18 mM) groups[2]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
||||||||||||||||
分子量 |
188.13 |
||||||||||||||||
Formula |
C7H8O6 |
||||||||||||||||
CAS 号 |
5995-86-8 |
||||||||||||||||
中文名称 |
没食子酸-水合物 |
||||||||||||||||
运输条件 |
Room temperature in continental US; may vary elsewhere. |
||||||||||||||||
储存方式 |
|
||||||||||||||||
溶解性数据 |
In Vitro:
DMSO : 50 mg/mL (265.77 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
|
||||||||||||||||
参考文献 |
|
所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务