Trichloroacetic acid

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Trichloroacetic acid  纯度: ≥95.0%

Trichloroacetic acid 是一种常用的面部表面修复剂。Trichloroacetic acid 是三氯乙烯的代谢产物，被认为有助于其在小鼠体内的肝癌效应。

Trichloroacetic acid

Trichloroacetic acid Chemical Structure

CAS No. : 76-03-9

规格 价格 是否有货 数量
500 mg ￥350 In-stock
1 g   询价  
5 g   询价  

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生物活性

Trichloroacetic acid is a commonly utilized agent for chemical resurfacing of the face. Trichloroacetic acid is a metabolite of trichloroethylene thought to contribute to its hepatocarcinogenic effects in mice[1][2].

IC50 & Target

Human Endogenous Metabolite

 

体外研究
(In Vitro)

Trichloroacetic acid (TCA) is a common drinking water disinfection byproduct that produces a spectrum of liver effects, including hepatomegaly and liver tumors, in mice. It is also an oxidative metabolite of trichloroethylene (TCE), a solvent used in degreasing with widespread environmental exposure, which also produces hepatomegaly and liver tumors in mice[3].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

163.39

Formula

C2HCl3O2
CAS 号

76-03-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献

  • [1]. Herbig K, et al. Combination Jessner’s solution and trichloroacetic acid chemical peel: technique and outcomes. Plast Reconstr Surg. 2009;124(3):955-964.

    [2]. Stenner RD, et al. Enterohepatic recirculation of trichloroethanol glucuronide as a significant source of trichloroacetic acid. Metabolites of trichloroethylene. Drug Metab Dispos. 1997;25(5):529-535.

    [3]. Chiu WA. Trichloroacetic acid: updated estimates of its bioavailability and its contribution to trichloroethylene-induced mouse hepatomegaly. Toxicology. 2011;285(3):114-125.

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