p32 Inhibitor M36(Synonyms: M36)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

p32 Inhibitor M36 (Synonyms: M36) 纯度: ≥98.0%

p32 inhibitor M36 (M36) 是一种 p32 线粒体蛋白小分子抑制剂，可直接与 p32 结合，抑制 p32 与 LyP-1 的结合。

p32 Inhibitor M36(Synonyms: M36)

p32 Inhibitor M36 Chemical Structure

CAS No. : 802555-85-7

规格 价格 是否有货 数量
10 mM * 1 mL in DMSO ￥5230 In-stock
1 mg ￥1600 In-stock
5 mg ￥5300 In-stock
10 mg ￥7500 In-stock
25 mg ￥12500 In-stock
50 mg ￥18750 In-stock
100 mg ￥28000 In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

p32 Inhibitor M36 相关产品

•相关化合物库:

  • Covalent Screening Library Plus
  • Bioactive Compound Library Plus
  • Epigenetics Compound Library
  • Kinase Inhibitor Library
  • TGF-beta/Smad Compound Library
  • Anti-Cancer Compound Library
  • Covalent Screening Library
  • Reprogramming Compound Library
  • Oxygen Sensing Compound Library
  • Cytoskeleton Compound Library

生物活性

p32 inhibitor M36 (M36) is a p32 mitochondrial protein inhibitor, which binds directly to p32 and inhibits p32 association with LyP-1[1].

IC50 & Target

p32[1]
体外研究
(In Vitro)

p32 Inhibitor M36 inhibits SF188 glioma cells proliferation (IC50 of 77.9 μM in complete media) and is much more potent under low glucose conditions with an IC50 of 7.3 μM[1].
p32 Inhibitor M36 is selective for p32 overexpressing cells[1].
p32 Inhibitor M36 is also a potent inhibitor of patient-derived neurospheres with an IC50 of 2.8 μM[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

448.52

Formula

C23H28N8O2
CAS 号

802555-85-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

DMSO : 5 mg/mL (11.15 mM; ultrasonic and warming and heat to 80°C)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.2296 mL 11.1478 mL 22.2956 mL
5 mM 0.4459 mL 2.2296 mL 4.4591 mL
10 mM 0.2230 mL 1.1148 mL 2.2296 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Yenugonda V,et al. A novel small molecule inhibitor of p32 mitochondrial protein overexpressed in glioma. J Transl Med. 2017 Oct 18;15(1):210.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务