CD3254

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

CD3254  纯度: 98.13%

CD3254 是一种有效的选择性类视黄醇 X 受体 (RXR) 激动剂。

CD3254

CD3254 Chemical Structure

CAS No. : 196961-43-0

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg)   Apply now  
10 mM * 1 mL in DMSO ￥1100 In-stock
5 mg ￥1000 In-stock
10 mg ￥1600 In-stock
25 mg ￥3200 In-stock
50 mg ￥5400 In-stock
100 mg   询价  
200 mg   询价  

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生物活性

CD3254 a potent and selective retinoid-X-receptor (RXR) agonist[1].

IC50 & Target[1]

RXR

 

体外研究
(In Vitro)

CD3254 induces similar phenotypes of malformations after 5 days exposure at low concentration (20 μg/L) to those after the 1st d exposure at high concentrations (50 and 100 μg/L)[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: zebrafish (Danio rerio) embryos
Concentration: 10, 20, 50, 100 μg/L
Incubation Time:
Result: The percent of survival decreased by 19.1 % in 100 μg/L CD3254-treated group after the 1st day exposure. The embryos did not hatch in groups exposed to 100 μg/L CD3254 for 5 days or to 1 mg/L CD3254 for the 1st day.

分子量

364.48

Formula

C24H28O3
CAS 号

196961-43-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

DMSO : 125 mg/mL (342.95 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.7436 mL 13.7182 mL 27.4363 mL
5 mM 0.5487 mL 2.7436 mL 5.4873 mL
10 mM 0.2744 mL 1.3718 mL 2.7436 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Nahoum V, et al. Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function. Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17323-8.

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