SuO-Val-Cit-PAB-MMAE

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

SuO-Val-Cit-PAB-MMAE  纯度: 98.70%

SuO-Val-Cit-PAB-MMAE 是抗体偶联药物的一部分 (drug-linker conjugate for ADC)。由肽段 SuO-Val-Cit-PAB 和抗有丝分裂剂 MMAE (一种 tubulin 抑制剂) 连接而成。

SuO-Val-Cit-PAB-MMAE

SuO-Val-Cit-PAB-MMAE Chemical Structure

规格 价格 是否有货 数量
1 mg ￥3500 In-stock
5 mg ￥8500 In-stock
10 mg ￥13500 In-stock
50 mg   询价  
100 mg   询价  

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生物活性

SuO-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the peptide SuO-Val-Cit-PAB[1].

IC50 & Target

Auristatin

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1264.51

Formula

C63H97N11O16
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-80°C, stored under nitrogen

*该产品在溶液状态不稳定，建议您现用现配，即刻使用。
参考文献

  • [1]. Kamath AV, et al. Preclinical Pharmacokinetic Considerations for the Development of Antibody Drug Conjugates. Pharm Res. 2015 Nov;32(11):3470-9.

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