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Artemether (Synonyms: 蒿甲醚; Dihydroqinghaosu methyl ether; Dihydroartemisinin methyl ether; SM224) 纯度: ≥98.0%
Artemether是抗疟疾化合物,可作用于恶性疟疾的耐药株。
Artemether Chemical Structure
CAS No. : 71963-77-4
规格 | 价格 | 是否有货 | 数量 |
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Free Sample (0.1-0.5 mg) | Apply now | ||
10 mM * 1 mL in DMSO | ¥550 | In-stock | |
100 mg | ¥500 | In-stock | |
500 mg | ¥990 | In-stock | |
1 g | 询价 | ||
5 g | 询价 |
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Artemether 相关产品
•相关化合物库:
- Covalent Screening Library Plus
- Natural Product Library Plus
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- FDA-Approved Drug Library Plus
- FDA-Approved Drug Library Mini
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- Children’s Drug Library
生物活性 |
Artemether is an antimalarial for the treatment of resistant strains of falciparum malaria. Target: Antiparasitic Artemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy. Artemether exhibits the highest activity against juvenile stages of the parasites, while adult worms are significantly less susceptible. There was no indication of neurotoxicity following repeated high doses of artemether given fortnightly for up to 5 months. Artemether-integrated with other control strategies-has considerable potential for reducing the current burden of schistosomiasis in different epidemiological settings [1]. There were remarkably inhibitory effects of artmeter on brain glioma growth and angiogenesis in SD rats and the mechanism that artemether inhibited brain glioma growth might be penetrating the blood-brain barrier and inhibiting angiogenesis [2]. |
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Clinical Trial |
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分子量 |
298.37 |
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Formula |
C16H26O5 |
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CAS 号 |
71963-77-4 |
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中文名称 |
蒿甲醚;青蒿醚 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 100 mg/mL (335.15 mM; Need ultrasonic) H2O : < 0.1 mg/mL (insoluble) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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