Triphala(Synonyms: 三果宝)

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Triphala (Synonyms: 三果宝)

Triphala 是阿育吠陀的多草药配方，Triphala 由三种草本植物 Terminalia chebula，Terminalia bellerica，和 Phyllanthus emblica 组成。Triphala 抑制 NF-κB 活化。Triphala 发挥抗真菌 (antifungal) 作用。具有抗脂肪形成，抗炎，抗肿瘤效果。

Triphala(Synonyms: 三果宝)

Triphala Chemical Structure

CAS No. : 857906-76-4

规格 价格 是否有货
10 mg (10 mg/mL in Water) ￥660 询问价格 & 货期

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生物活性

Triphala, an Ayurvedic polyherbal formulation comprising of equiproportional fruit parts of Terminalia chebula, Terminalia bellerica, and Phyllanthus emblica[1]. Triphala inhibits NF-κB activation. Triphala exerts antifungal action[2]. Anti-adipogenic, anti-inflammatory, and anti-neoplastic activities.

IC50 & Target[2]

NF-κB

 

Antifungal

 

体外研究
(In Vitro)

Triphala regulates adipogenesis through modulation of expression of adipogenic genes in 3T3-L1 cell line. Triphala significantly decreases the adipogenesis in 3T3-L1 cells by reducing lipid accumulation and inhibiting the expression of adipogenic genes. The 3T3-L1 cells treated with Triphala show ~1.43-, 1.67-, and 2.5-fold decreases in lipid content at 1, 10, and 100 μg/mL concentrations, respectively, compared to the cells treated with induction cocktail alone. Triphala regulates lipid accumulation by down regulating expression of adipogenic genes, resulting into prevention of adipogenesis[1].
Triphala reduces expression of inflammatory mediators such as IL-17, COX-2, and RANKL through inhibition of NF-κB activation[2]. Triphala exerts antifungal action against Asperigillus species and has been reported to inhibit the fungus by up to 37.96% in vitro[2].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial

CAS 号

857906-76-4
中文名称

三果宝
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献

  • [1]. Banjare J, et al. Triphala, Regulates Adipogenesis through Modulation of Expression of Adipogenic Genes in 3T3-L1 Cell Line. Pharmacogn Mag. 2018 Jan;13(Suppl 4):S834-S839.

    [2]. Peterson CT, et al. Therapeutic Uses of Triphala in Ayurvedic Medicine. J Altern Complement Med. 2017 Aug;23(8):607-614.

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