MethADP(Synonyms: Adenosine 5′-(α,β-methylene)diphosphate)

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MethADP (Synonyms: Adenosine 5′-(α,β-methylene)diphosphate)

MethADP 是一个特异性的 CD73 抑制剂。

MethADP(Synonyms: Adenosine 5

MethADP Chemical Structure

CAS No. : 3768-14-7

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生物活性

MethADP is a specific CD73 inhibitor.

IC50 & Target

CD73[1].
体外研究
(In Vitro)

MethADP (AMP-CP: 20 μM) causes a marked inhibition of adenosine formation (0.96±0.96 μM) compared to untreated controls (9.6±1.5 μM) in A498 and RT4 cells, and MethADP (100 μM) completely inhibits the adenosine formation[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

425.23

Formula

C11H17N5O9P2
CAS 号

3768-14-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Mohlin C, et al. Studies of the extracellular ATP-adenosine pathway in human urinary tract epithelial cells. Pharmacology. 2009;84(4):196-202.

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