LY 222306

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LY 222306 

LY 222306是甘氨酰胺核糖核苷酸甲酰转移酶 ((GARFT)) 的抑制剂,Ki 值为0.77 nM。

LY 222306

LY 222306 Chemical Structure

CAS No. : 154446-98-7

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生物活性

LY 222306 is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor with a Ki of 0.77 nM.

IC50 & Target

Ki: 0.77 nM (GARFT)[1]

分子量

433.42

Formula

C19H23N5O7

CAS 号

154446-98-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Habeck LL, et al. A novel class of monoglutamated antifolates exhibits tight-binding inhibition of human glycinamide ribonucleotide formyltransferase and potent activity against solid tumors. Cancer Res. 1994 Feb 15;54(4):1021-6.

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