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Thalidomide-O-amido-C8-NH2 (Synonyms: Cereblon Ligand-Linker Conjugates 2; E3 Ligase Ligand-Linker Conjugates 20)
Thalidomide-O-amido-C8-NH2 (Cereblon Ligand-Linker Conjugates 2) 是一种合成的 E3 连接酶配体-linker 偶联物，包含基于 Thalidomide 的 cereblon 配体和 1 个 linker。可用于合成 PROTAC 分子。
Thalidomide-O-amido-C8-NH2 Chemical Structure
CAS No. : 1950635-15-0
| 规格 | 是否有货 | ||
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| 100 mg | 询价 | ||
| 250 mg | 询价 | ||
| 500 mg | 询价 |
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Thalidomide-O-amido-C8-NH2 的其他形式现货产品:
| 生物活性 |
Thalidomide-O-amido-C8-NH2 (Cereblon Ligand-Linker Conjugates 2), a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1]. |
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| IC50 & Target[1] |
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| 体外研究 (In Vitro) |
Thalidomide-O-amido-C8-NH2 is a degron-linker (refer to Compound DL7-TL). The PROTAC linker is bound lo at least one targeting ligand. Degron-linker-targeting ligand, wherein the linker is covalently bound lo at least one degron and at least one targeting ligand, the degron is a compound capable of binding to an ubiquitin ligase such as an E3 ubiquitin ligase (e g, cereblon), and the targeting ligand is capable of binding to the targeted protein (s)[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
458.51 |
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| Formula |
C23H30N4O6 |
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| CAS 号 |
1950635-15-0 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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| 参考文献 |
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