24-Methylenecycloartanyl ferulate

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24-Methylenecycloartanyl ferulate 

24-Methylenecycloartanyl ferulate 是一种 γ-谷维素化合物。24-Methylenecycloartanyl ferulate 能促进人乳腺癌细胞中的 parvin-beta 的表达。24-Methylenecycloartanyl ferulate 是潜在的 ATP 竞争性的 Akt1 抑制剂 (EC50= 33.3μM)。

24-Methylenecycloartanyl ferulate

24-Methylenecycloartanyl ferulate Chemical Structure

CAS No. : 469-36-3

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生物活性

24-Methylenecycloartanyl ferulate is a γ-oryzanol compound. 24-Methylenecycloartanyl ferulate promotes parvin-beta expression in human breast cancer cells. 24-Methylenecycloartanyl ferulate is a potential ATP-competitive Akt1 inhibitor (EC50= 33.3μM)[1].

IC50 & Target

Akt1

33.3 μM (EC50)

分子量

616.91

Formula

C41H60O4

CAS 号

469-36-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Heon Woong Kim, et al. 24-Methylenecycloartanyl ferulate, a major compound of γ-oryzanol, promotes parvin-beta expression through an interaction with peroxisome proliferator-activated receptor-gamma 2 in human breast cancer cells. Biochem Biophys Res Commun. 2015 Dec 25;468(4):574-9.

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