Aldose reductase-IN-4

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Aldose reductase-IN-4 

Aldose reductase-IN-4 (comund IIc) 是一种醛糖还原酶 (aldose reductase) 抑制剂,对醛还原酶 1 (ALR1) 和 ALR2IC50 分别为 11.70 μM 和 0.98 μM。

Aldose reductase-IN-4

Aldose reductase-IN-4 Chemical Structure

CAS No. : 2446136-17-8

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生物活性

Aldose reductase-IN-4 (compund IIc) is an aldose reductase inhibitor with IC50s of 11.70 μM and 0.98 μM for aldehyde reductase 1 (ALR1) and ALR2, respectively[1].

IC50 & Target

IC50: 11.70 μM (Aldehyde reductase 1) and 0.98 μM (Aldehyde reductase 2)[1]

分子量

291.30

Formula

C14H10FNO3S

CAS 号

2446136-17-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Konstantinos Koutsopoulos, et al. Design synthesis and evaluation of novel aldose reductase inhibitors: The case of indolyl-sulfonyl-phenols. Bioorg Med Chem. 2020 Aug 1;28(15):115575.

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