上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
ZIKV-IN-1
ZIKV-IN-1 是一种有效的 zika virus 抑制剂,EC50 为 2.8 µM,EC90 为 6.8 µM。ZIKV-IN-1 显示出抗 ZIKV 活性,且具有低细胞毒性。ZIKV-IN-1 对 ZIKV RdRp 结构域具有很强的亲和力。
ZIKV-IN-1 Chemical Structure
CAS No. : 2762166-06-1
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生物活性 |
ZIKV-IN-1 is a potent zika virus inhibitor with an EC50 of 2.8 µM and EC90 of 6.8 µM. ZIKV-IN-1 shows anti-ZIKV activity with low cytotoxicity. ZIKV-IN-1 shows a strong affinity to ZIKV RdRp domain[1]. |
IC50 & Target |
EC50: 2.8 µM (ZIKV)[1] |
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体外研究 (In Vitro) |
ZIKV-IN-1 (compound 38) (0-80 µM) shows anti-ZIKV activity in a dose-dependent manner in A549 cells[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability Assay[1]
Western Blot Analysis[1]
Cell Cytotoxicity Assay[1]
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分子量 |
478.29 |
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Formula |
C21H18BrF2N3O3 |
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CAS 号 |
2762166-06-1 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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参考文献 |
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