Lurtotecan(Synonyms: GI147211; OSI-211)

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Lurtotecan (Synonyms: GI147211; OSI-211)

Lurtotecan (GI147211; OSI-211) 是一种半合成喜树碱类似物,是一种拓扑异构酶 I (topoisomerase I) 抑制剂。Lurtotecan 具有抗癌作用。

Lurtotecan(Synonyms: GI147211;  OSI-211)

Lurtotecan Chemical Structure

CAS No. : 149882-10-0

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生物活性

Lurtotecan (GI147211; OSI-211), a semisynthetic Camptothecin analog, is a topoisomerase I inhibitor. Lurtotecan has anticancer effects[1].

IC50 & Target[1]

Topoisomerase I

 

分子量

518.56

Formula

C28H30N4O6

CAS 号

149882-10-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. D L Emerson, et al. In vivo antitumor activity of two new seven-substituted water-soluble camptothecin analogues. Cancer Res. 1995 Feb 1;55(3):603-9.

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