L-Norleucine-d9(Synonyms: (S)-2-Aminohexanoic acid-d9; (S)-Norleucine-d9)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

L-Norleucine-d9 (Synonyms: (S)-2-Aminohexanoic acid-d9; (S)-Norleucine-d9)

L-Norleucine-d9 ((S)-2-Aminohexanoic acid-d9) 是 L-Norleucine 的氘代物。L-Norleucine ((S)-2-Aminohexanoic acid) 是亮氨酸的异构体，能够影响骨骼肌中蛋白质的合成。

L-Norleucine-d9(Synonyms: (S)-2-Aminohexanoic acid-d9; (S)-Norleucine-d9)

L-Norleucine-d9 Chemical Structure

CAS No. : 1331889-36-1

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生物活性

L-Norleucine-d9 ((S)-2-Aminohexanoic acid-d9) is the deuterium labeled L-Norleucine. L-Norleucine ((S)-2-Aminohexanoic acid) is an isomer of leucine, specifically affects protein synthesis in skeletal muscle, and has antivirus activity.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

140.23

Formula

C6H4D9NO2
CAS 号

1331889-36-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Schott KJ, et al. On the role of branched-chain amino acids in protein turnover of skeletal muscle. Studies in vivo with L-norleucine. Z Naturforsch C. 1985 May-Jun;40(5-6):427-37.

    [3]. He T, et al. The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis. Oncogene. 2018 Jun 20.

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