Isoxanthohumol(Synonyms: 异黄腐醇；异黄腐酚)

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Isoxanthohumol (Synonyms: 异黄腐醇；异黄腐酚)

Isoxanthohumol 是从啤酒花和啤酒中提取的一种类黄酮。Isoxanthohumol 对多种人类癌细胞具有抗增殖活性。Isoxanthohumol 能抑制肿瘤动物肺转移灶的发展。Isoxanthohumol 对疱疹病毒 (HSV1和HSV2) 和牛病毒性腹泻病毒 (BVDV) 具有抗病毒活性。

Isoxanthohumol(Synonyms: 异黄腐醇；异黄腐酚)

Isoxanthohumol Chemical Structure

CAS No. : 521-48-2

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生物活性

Isoxanthohumol is a prenylflavonoid from hops and beer. Isoxanthohumol exhibits an antiproliferative activity against several human cancer cell lines. Isoxanthohumol inhibits the development of lung metastatic foci in tumor-challenged animals. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV)[1][2].

IC50 & Target

HSV-1

 

HSV-2

 

分子量

354.40

Formula

C21H22O5
CAS 号

521-48-2
中文名称

异黄腐醇；异黄腐酚
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Żołnierczyk AK, et al. Isoxanthohumol–Biologically active hop flavonoid. Fitoterapia. 2015 Jun;103:71-82.

    [2]. Krajnović T, et al. The hop-derived prenylflavonoid isoxanthohumol inhibits the formation of lung metastasis in B16-F10 murine melanoma model. Food Chem Toxicol. 2019 Jul;129:257-268.

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