Anticancer agent 33

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Anticancer agent 33 

Anticancer agent 33 (compound 3) 是一种 Squamocin 和 Bullatacin 衍生物,一种有效的抗癌剂。Anticancer agent 33 抑制 4T1 乳腺癌细胞系 (A549、HeLa、HepG2 和 MCF-7 细胞) 生长,IC50 为 1.9-5.4 µM。

Anticancer agent 33

Anticancer agent 33 Chemical Structure

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生物活性

Anticancer agent 33 (compound 3), a Squamocin and Bullatacin derivative, is a potent anticancer agent. Anticancer agent 33 shows high potency to inhibit 4T1 breast cancer cell line (A549, HeLa, HepG2 and MCF-7 cells) growth with IC50s of 1.9-5.4 µM[1].

分子量

877.20

Formula

C49H84N2O11

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Jing-Fang Shi, et al. Synthesis and anticancer activity of Boc-Gly-Pro dipeptide-annonaceous acetogenin prodrugs targeting fibroblast activation protein or other hydrolytic enzymes. Medicinal Chemistry Research volume 31, pages605–616 (2022).

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