Carbonic anhydrase inhibitor 9

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Carbonic anhydrase inhibitor 9 

Carbonic anhydrase inhibitor 9 是一种有效的碳酸酐酶 (CA) 抑制剂，对 hCA II 和 IX 的 Ki 分别为 56.4 和 56.9 nM。 具有抗增殖活性。

Carbonic anhydrase inhibitor 9

Carbonic anhydrase inhibitor 9 Chemical Structure

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生物活性

Carbonic anhydrase inhibitor 9 is a potent carbonic anhydrase (CA) inhibitor with Kis of 56.4 and 56.9 nM for hCA II and IX, respectively. Antiproliferative activity[1].

体外研究
(In Vitro)

Carbonic anhydrase inhibitor 9 (compound 3c) exerts only cytotoxic activity against A549 cell line with IC50=5.90 μM[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

530.39

Formula

C22H20BrN5O4S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Said MF, et al. Synthesis, molecular modelling and QSAR study of new N-phenylacetamide-2-oxoindole benzensulfonamide conjugates as carbonic anhydrase inhibitors with antiproliferative activity. J Enzyme Inhib Med Chem. 2022;37(1):701-717.

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