EGFR-IN-28

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

EGFR-IN-28 

EGFR-IN-28 是一种有效的 EGFR 抑制剂。EGFR-IN-28 具有抗肿瘤活性。

EGFR-IN-28

EGFR-IN-28 Chemical Structure

CAS No. : 2754392-31-7

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生物活性

EGFR-IN-28 is a potent EGFR inhibitor. EGFR-IN-28 has antitumor activity[1].

IC50 & Target[1]

EGFR

 

体外研究
(In Vitro)

EGFR-IN-28 inhibits Δ19Del, L858R, Δ19Del/T790M, L858R/T790M, Δ19Del/T790M/C797S, L858R/T790M/C797S (all IC50s≤50nM)[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

711.68

Formula

C31H39BrN10O3S

CAS 号

2754392-31-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Xianming Deng, et al. EGFR inhibitor, preparation method and application thereof. WO2021238827A1.

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