Teleocidin A1(Synonyms: Lyngbyatoxin A)

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Teleocidin A1 (Synonyms: Lyngbyatoxin A)

Teleocidin A1 (Lyngbyatoxin A) 是一种剧毒皮肤刺激物,是蛋白激酶C (PKC) 的有效激活剂。Teleocidin A1 对 HeLa 癌细胞具有抗增殖活性 (IC50=9.2 nM)。

Teleocidin A1(Synonyms: Lyngbyatoxin A)

Teleocidin A1 Chemical Structure

CAS No. : 70497-14-2

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生物活性

Teleocidin A1 (Lyngbyatoxin A), a highly toxic skin irritant, is a potent activator of protein kinase C (PKC). Teleocidin A1 shows antiproliferative activity against HeLa cancer cells (IC50=9.2 nM)[1][2].

分子量

437.62

Formula

C27H39N3O2

CAS 号

70497-14-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Stafford RG, et al. Comparison of the partition coefficient and skin penetration of a marine algal toxin (lyngbyatoxin A). Food Chem Toxicol. 1992;30(9):795-801.

    [2]. Youssef DT, Shaala LA, Mohamed GA, et al. 2,3-seco-2,3-dioxo-lyngbyatoxin A from a Red Sea strain of the marine cyanobacterium Moorea producens. Nat Prod Res. 2015;29(8):703-709.

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