Sanggenol L

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Sanggenol L 

Sanggenol L 诱导依赖和非依赖 caspase 的黑素瘤皮肤癌细胞凋亡。 Sanggenol L 通过抑制前列腺癌细胞 PI3K/Akt/mTOR 信号通路诱导细胞凋亡,通过激活前列腺癌细胞 p53 诱导细胞周期停滞。

Sanggenol L

Sanggenol L Chemical Structure

CAS No. : 329319-20-2

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生物活性

Sanggenol L induces caspase-dependent and caspase-independent apoptosis in melanoma skin cancer cells[1]. Sanggenol L induces of apoptosis via suppression of PI3K/Akt/mTOR signaling and cell cycle arrest via activation of p53 in p

分子量

422.47

Formula

C25H26O6

CAS 号

329319-20-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Won YS, Seo KI. Sanggenol L promotes apoptotic cell death in melanoma skin cancer cells through activation of caspase cascades and apoptosis-inducing factor. Food Chem Toxicol. 2020;138:111221.

    [2]. Won YS, Seo KI. Sanggenol L Induces Apoptosis and Cell Cycle Arrest via Activation of p53 and Suppression of PI3K/Akt/mTOR Signaling in Human Prostate Cancer Cells. Nutrients. 2020;12(2):488. Published 2020 Feb 14.

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