Thalidomide-5-propoxyethanamine

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Thalidomide-5-propoxyethanamine 

Thalidomide-5-propoxyethanamine 是基于Thalidomide 的 CRBN 配体,用于CRBN 蛋白招募。

Thalidomide-5-propoxyethanamine

Thalidomide-5-propoxyethanamine Chemical Structure

CAS No. : 2357107-60-7

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生物活性

Thalidomide-5-propoxyethanamine is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein[1].

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

359.38

Formula

C18H21N3O5

CAS 号

2357107-60-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Mainolfi, Nello, et al. IRAK DEGRADERS AND USES THEREOF. Patent US20190192668A1.

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