IL-4-inhibitor-1

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

IL-4-inhibitor-1 

IL-4-inhibitor-1 (compound 52) 是 IL-4 的抑制剂，其 EC50 值为 1.81 µM。

IL-4-inhibitor-1

IL-4-inhibitor-1 Chemical Structure

CAS No. : 1332184-63-0

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5 mg 询价
50 mg 询价

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生物活性

IL-4-inhibitor-1 (compound 52) is an IL-4 inhibitor, with an EC50 of 1.81 µM[1].

IC50 & Target

EC50: 1.81 µM (IL-4)[1].
体外研究
(In Vitro)

IL-4-inhibitor-1 (compound 52) displays low micromolar affinity and exhibits functional disruption of type II IL-4 binding in a cellular context[1].
IL-4-inhibitor-1 (compound 52) exhibits dose-dependent reduction in pSTAT-6 levels with an EC50 value of 3.1 µM, but did not affect the levels of STAT-6[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

321.31

Formula

C18H12FN3O2
CAS 号

1332184-63-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Sean P Quinnell, et al. A Small-Molecule Inhibitor to the Cytokine Interleukin-4. ACS Chem Biol. 2020 Oct 16;15(10):2649-2654.

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