IDH-C227

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

IDH-C227 

IDH-C227 是一种有效的选择性 IDH1R132H 抑制剂。IDH-C227 具有抗癌作用。

IDH-C227

IDH-C227 Chemical Structure

CAS No. : 1355324-14-9

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生物活性

IDH-C227 is a potent and selective IDH1R132H inhibitor. IDH-C227 has anticancer effcts[1].

体外研究
(In Vitro)

IDH-C227 shows anticancer effcts, with IC50 values of <0.1 μM and 0.25 μM against HT1080 and U87MG cells, respectively[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

498.59

Formula

C30H31FN4O2

CAS 号

1355324-14-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Hanumantha Rao Madala, et al. Beyond Brooding on Oncometabolic Havoc in IDH-Mutant Gliomas and AML: Current and Future Therapeutic Strategies. Cancers (Basel). 2018 Feb 11;10(2):49.

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