Prosaikogenin F(Synonyms: 前柴胡皂苷F)

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Prosaikogenin F (Synonyms: 前柴胡皂苷F)

Prosaikogenin F 是一种具有抗癌和溶血特性的单糖苷。

Prosaikogenin F(Synonyms: 前柴胡皂苷F)

Prosaikogenin F Chemical Structure

CAS No. : 99365-20-5

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生物活性

Prosaikogenin F is a monoglycoside with anticancer and hemolytic properties[1][2].

体外研究
(In Vitro)

Prosaikogenin F inhibits A549 proliferation with inhibition rates of 40.53%, 92.62% and 93.07% at concentrations of 20, 40 and 60 μg/mL, respectively[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

In mice, intraperitoneal administration of Saikosaponin A and its intestinal metabolite, Prosaikogenin F, show corticosterone secretion-inducing activity at a dose of 0.1 mmol/kg, and maximally increase it at a dose of 0.4 mmol/kg[3].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

618.84

Formula

C36H58O8

CAS 号

99365-20-5

中文名称

前柴胡皂苷F

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Lu Shi, et al. A Potential Anti-cancer Compound Separated from the Chloroform Extract of the Chinese Medicine Formula Shenqi San. Curr Med Sci. 2020 Feb;40(1):138-144.

    [2]. M Nose, S Amagaya, et al. Effects of saikosaponin metabolites on the hemolysis of red blood cells and their adsorbability on the cell membrane. Chem Pharm Bull (Tokyo). 1989 Dec;37(12):3306-10.

    [3]. M Nose, et al. Corticosterone secretion-inducing activity of saikosaponin metabolites formed in the alimentary tract. Chem Pharm Bull (Tokyo). 1989 Oct;37(10):2736-40.

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