Malvidin-3-galactoside chloride(Synonyms: 氯化锦葵色素-3-O-半乳糖苷)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Malvidin-3-galactoside chloride (Synonyms: 氯化锦葵色素-3-O-半乳糖苷)

Malvidin-3-galactoside chloride 是一种花青素单体,可诱导肝细胞癌 (HCC) 细胞周期停滞和凋亡。Malvidin-3-galactoside chloride 抑制 ROS 的产生和积累。Malvidin-3-galactoside chloride 具有抗肿瘤功能。

Malvidin-3-galactoside chloride(Synonyms: 氯化锦葵色素-3-O-半乳糖苷)

Malvidin-3-galactoside chloride Chemical Structure

CAS No. : 30113-37-2

规格 价格 是否有货
1 mg ¥3360 询问价格 & 货期
5 mg ¥10000 询问价格 & 货期
10 mg ¥15840 询问价格 & 货期

* Please select Quantity before adding items.

生物活性

Malvidin-3-galactoside chloride, an anthocyanin monomer, induces hepatocellular carcinoma (HCC) cells cycle arrest and apoptosis. Malvidin-3-galactoside chloride inhibits the production and accumulation of ROS. Malvidin-3-galactoside chloride has anti-tumor function[1].

体外研究
(In Vitro)

Malvidin-3-galactoside chloride (50, 100, 200 μg/mL; for 24, 48, 72 h) displays obvious cytotoxicity on Huh-7 cells and has no significant effect with 50 and 100 μg/mL for 48 h. Malvidin-3-galactoside chloride has a notable cytotoxic effect against Huh-7 cells at 72 h[1].
Malvidin-3-galactoside chloride (50-200 μg/mL) arrests the cells in the S phase, accompanied by the cells in the G1 phase decreased, and the cells in the S phase increased[1].
Malvidin-3-galactoside chloride (50-200 μg/mL; for 72 h) induces cell apoptosis in Huh-7 cells[1].
Malvidin-3-galactoside chloride (50-200 μg/mL; for 72 h) markedly increased the levels of caspase-3, cleaved-caspase-3 and cleaved-PARP in a dose-dependent manner[1].
Malvidin-3-galactoside chloride (50-200 μg/mL; for 12 h) inhibits the production and accumulation of ROS[1].
Malvidin-3-galactoside chloride (50-200 μg/mL; for 12 h) dramatically reduces the level of phosphorylation ERK (p-ERK) in a dose-dependent manner. Malvidin-3-galactoside chloride with 200 μg/mL markedly increases the phosphorylation level of p38 and JNK (p-p38 and p-JNK)[1].
Malvidin-3-galactoside chloride (50-200 μg/mL; for 12 h) inhibits the migration and invasion in Huh-7 cells[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

528.89

Formula

C23H25ClO12

CAS 号

30113-37-2

中文名称

氯化锦葵色素-3-O-半乳糖苷

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Jie Lin, et al. Malvidin-3-galactoside from blueberry suppresses the growth and metastasis potential of hepatocellular carcinoma cell Huh-7 by regulating apoptosis and metastases pathways. Food Science and Human Wellness, Volume 9, Issue 2, June 2020, Pages 136-145.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务