Malvidin chloride(Synonyms: Syringidin)

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Malvidin chloride (Synonyms: Syringidin)

Malvidin (chloride) 是一种从 Oryza sativacv. Heugjinjubyeo 中分离出来的生物活性化合物。 Malvidin 通过阻止细胞周期的 G2/M 期和诱导细胞凋亡显示出细胞毒性。Malvidin可用于癌症研究。

Malvidin chloride(Synonyms: Syringidin)

Malvidin chloride Chemical Structure

CAS No. : 643-84-5

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生物活性

Malvidin (chloride) is a bioactive compound isolated from Oryza sativacv. Heugjinjubyeo. Malvidin shows cytotoxicity through the arrest of the G2/M phase of cell cycle and induction of apoptosis. Malvidin can be used for the research of cancer[1].

体外研究
(In Vitro)

Malvidin (0~80 μg/mL; 96 hours; U937 cells) shows cytotoxic activity in a dose-dependent pattern[1].
The IC50 value of Malvidin for U937 cells is 40 μg/mL. Malvidin (U937 cells) shows arrest at the G2/M phase of the cell cycle and increases sub G1 hypo-diploid population[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: U937 cells
Concentration: 0~80 μg/mL
Incubation Time: 96 hours
Result: Showed cytotoxic activity in a dose-dependent pattern.

分子量

366.75

Formula

C17H15ClO7

CAS 号

643-84-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Jin W H, et al. Cyanidin and Malvidin fromOryza sativacv. HeugjinjubyeoMediate Cytotoxicity against Human Monocytic Leukemia Cellsby Arrest of G2/M Phase and Induction of Apoptosis. J. Agric. Food Chem. 2004, 52, 8, 2213–2217

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