Cinchonine monohydrochloride hydrate(Synonyms: (8R,9S)-Cinchonine monohydrochloride hydrate; LA40221 monohydrochloride hydrate)

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Cinchonine monohydrochloride hydrate (Synonyms: (8R,9S)-Cinchonine monohydrochloride hydrate; LA40221 monohydrochloride hydrate)

Cinchonine ((8R,9S)-Cinchonine) monohydrochloride hydrate 是一种天然化合物,已被有效用作抗疟剂。Cinchonine monohydrochloride hydrate 激活内质网应激诱导的人肝癌细胞凋亡。Cinchonine monohydrochloride hydrate 也是人血小板聚集的抑制剂。Cinchonine monohydrochloride hydrate 对脂肪生成具有抑制作用。

Cinchonine monohydrochloride hydrate(Synonyms: (8R,9S)-Cinchonine monohydrochloride hydrate; LA40221 monohydrochloride hydrate)

Cinchonine monohydrochloride hydrate Chemical Structure

CAS No. : 206986-88-1

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生物活性

Cinchonine ((8R,9S)-Cinchonine) monohydrochloride hydrate is a natural compound which has been effectively used as antimalarial agent. Cinchonine monohydrochloride hydrate activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Cinchonine monohydrochloride hydrate is also an inhibitor of human platelet aggregation. Cinchonine monohydrochloride hydrate possesses a suppressive effect on adipogenesis[1].

Formula

C19H22N2O.HCl.xH2O

CAS 号

206986-88-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Jin ZL, et, al. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Exp Ther Med. 2018 Jun;15(6):5046-5050.

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