Azido-PEG10-propargyl

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Azido-PEG10-propargyl 

Azido-PEG10-propargyl 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Azido-PEG10-propargyl

Azido-PEG10-propargyl Chemical Structure

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生物活性

Azido-PEG10-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

521.60

Formula

C23H43N3O10

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-998.

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