Propargyl-PEG13-Boc

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Propargyl-PEG13-Boc 

Propargyl-PEG13-Boc 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Propargyl-PEG13-Boc

Propargyl-PEG13-Boc Chemical Structure

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生物活性

Propargyl-PEG13-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

712.86

Formula

C34H64O15

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-995.

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