Isolimonexic acid

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Isolimonexic acid 

Isolimonexic acid 是从柠檬种子中分离得到的一种类柠檬酸,具有抗癌和抗芳香化酶 (anti-aromatase) (IC50=25.60 μM) 特性。

Isolimonexic acid

Isolimonexic acid Chemical Structure

CAS No. : 73904-93-5

规格 是否有货
5 mg 询价
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25 mg 询价

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生物活性

Isolimonexic acid is a limonoid isolated from lemon (Citrus lemon L. Burm) seed, has anti-cancer and anti-aromatase (IC50=25.60 μM) properties[1].

IC50 & Target

IC50: 25.60 μM (aromatase)[1]

体外研究
(In Vitro)

Isolimonexic acid (200 μM; 72 hours) exhibits cytotoxicity on MCF-7 cells and shows no cytotoxicity against the MDA-MB-231 cell lines[1].
Isolimonexic acid (50 μg/ml; 48, 96 and 144 hours) exhibits cell growth inhibition of Panc-28 cells in a time-dependent manner.And it percent inhibition comparison to control cells are 21%, 68%, and 90.58% at 48, 72, and 144 h, respectively[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

502.51

Formula

C26H30O10

CAS 号

73904-93-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Jinhee Kim, et al. Limonoids and their anti-proliferative and anti-aromatase properties in human breast cancer cells. Food Funct. 2013 Feb;4(2):258-65.

    [2]. Jaiprakash R Patil, et al.Bioactive compounds from Mexican lime ( Citrus aurantifolia ) juice induce apoptosis in human pancreatic cells. J Agric Food Chem. 2009 Nov 25;57(22):10933-42.

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