Toralactone(Synonyms: 决明内酯)

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Toralactone (Synonyms: 决明内酯)

Toralactone 可从Cassia obtusifolia 中分离得到，通过 Nrf2 依赖的抗氧化机制介导肝保护。

Toralactone(Synonyms: 决明内酯)

Toralactone Chemical Structure

CAS No. : 41743-74-2

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生物活性

Toralactone, isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism[1].

体外研究
(In Vitro)

Toralactone sensitize resistant MCF-7adr cell line to paclitaxel via inhibiting P-glycoprotein efflux activity[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

272.25

Formula

C15H12O5
CAS 号

41743-74-2
中文名称

决明内酯
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. YongtaekSeo, et al. Toralactone glycoside in Cassia obtusifolia mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism. Food Research International. Volume 97, July 2017, Pages 340-346.

    [2]. Salwa D. Alqahtani, et al. Abstract 1205: Rubrofusarin and toralactone sensitize resistant MCF-7adr cell line to paclitaxel via inhibiting P-glycoprotein efflux activity. AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC.

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