上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。
Bcl-2-IN-2
Bcl-2-IN-2 是一种有效的选择性 Bcl-2 抑制剂，IC50 为 0.034 nM，也可抑制 Bcl-xL，IC50 为 43 nM，对 Bcl-2 的活性是 Bcl-xL 的 1000多倍。
Bcl-2-IN-2 Chemical Structure
CAS No. : 2383085-86-5
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| 250 mg | 询价 | ||
| 500 mg | 询价 |
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| 生物活性 |
Bcl-2-IN-2 is a potent and selective Bcl-2 inhibitor with an IC50 of 0.034 nM and also inhibits Bcl-xL with an IC50 of 43 nM, showing >1000-fold selectivity for Bcl-2 over Bcl-xL[1]. |
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| IC50 & Target[1] |
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| 体外研究 (In Vitro) |
Bcl-2-IN-2 inhibits mutant Bcl-2-G101V with an IC50 of 1.2 nM. Bcl-2-IN-2 inhibits RS4;11 cellular proliferation with an IC50 of 1.9 nM[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
876.07 |
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| Formula |
C48H57N7O7S |
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| CAS 号 |
2383085-86-5 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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| 参考文献 |
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