Budesonide impurity C(Synonyms: 布地奈德杂质C)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Budesonide impurity C (Synonyms: 布地奈德杂质C)

Budesonide impurity C 是 Budesonide 的一种杂质。Budesonide 是一种吸入型糖皮质类固醇,一种具有口服活性的糖皮质激素受体 (glucocorticoid receptor) 激动剂。

Budesonide impurity C(Synonyms: 布地奈德杂质C)

Budesonide impurity C Chemical Structure

CAS No. : 1040085-99-1

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Budesonide impurity C is an impurity of Budesonide. Budesonide, an inhaled glucocortical steroid, is an orally active glucocorticoid receptor agonist[1][2].

体外研究
(In Vitro)

Budesonide is selective for human glucocorticoid receptor (hGR; EC50=45.7 pM) over mineralocorticoid receptors (EC50=7,620 pM) in CV-1 cells[1].
Budesonide (30 min prior to LPS) suppresses the activation of the NLRP3 inflammasome by LPS (100 ng/mL) plus ATP (5 mM) in macrophages (RAW 264.7 cells)[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

430.53

Formula

C25H34O6

CAS 号

1040085-99-1

中文名称

布地奈德杂质C

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Patrizia Ferraboschi, et al. Estimation and Characterisation of Budesonide Tablets Impurities. J Pharm Biomed Anal. 2008 Jul 15;47(3):636-40.

    [2]. Claudia Grossmann, et al. Transactivation via the Human Glucocorticoid and Mineralocorticoid Receptor by Therapeutically Used Steroids in CV-1 Cells: A Comparison of Their Glucocorticoid and Mineralocorticoid Properties. Eur J Endocrinol. 2004 Sep;151(3):397-406.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务