Biotin-PEG8-amine

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Biotin-PEG8-amine 

Biotin-PEG8-amine 是一种生物素标记的 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Biotin-PEG8-amine

Biotin-PEG8-amine Chemical Structure

CAS No. : 2183447-27-8

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生物活性

Biotin-PEG8-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

638.81

Formula

C28H54N4O10S

CAS 号

2183447-27-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

参考文献
  • [1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.

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