Azido-PEG5-PFP ester

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Azido-PEG5-PFP ester 

Azido-PEG5-PFP ester 是一种 PROTAC linker,属于 PEG 和 Alkyl/ether 类,可用于合成 PROTAC。

Azido-PEG5-PFP ester

Azido-PEG5-PFP ester Chemical Structure

CAS No. : 1818294-48-2

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

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生物活性

Azido-PEG5-PFP ester is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

501.40

Formula

C19H24F5N3O7

CAS 号

1818294-48-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.

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