Br-PEG4-CH2-Boc

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Br-PEG4-CH2-Boc 

Br-PEG4-CH2-Boc 是一种 PROTAC linker 属于 PEGAlkyl/ether 类,可用于合成 PROTAC 。

Br-PEG4-CH2-Boc

Br-PEG4-CH2-Boc Chemical Structure

CAS No. : 1807505-29-8

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生物活性

Br-PEG4-CH2-Boc is a PEG– and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

371.26

Formula

C14H27BrO6

CAS 号

1807505-29-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Darren H. Wakefield, et al. Poly(vinyl ester) Polymers for In Vivo Nucleic Acid Delivery. US20130121954A1.

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