Helichrysetin(Synonyms: 蜡菊亭; 4,2′,4′-三羟基-6′-甲氧基查耳酮)

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Helichrysetin (Synonyms: 蜡菊亭; 4,2′,4′-三羟基-6′-甲氧基查耳酮)

Helichrysetin,分离于 Helichrysum odoratissimum 的花朵中, 是一种ID2 (DNA 结合抑制剂 2) 抑制剂,可抑制DCIS (原位导管癌) 的形成。Helichrysetin 对细胞生长具有很强的抑制作用,并且能够诱导 A549 细胞凋亡 (apoptosis)。

Helichrysetin(Synonyms: 蜡菊亭; 4,2

Helichrysetin Chemical Structure

CAS No. : 62014-87-3

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生物活性

Helichrysetin, isolated from the flowers of Helichrysum odoratissimum, is an ID2 (inhibitor of DNA binding 2) inhibitor, and suppresses DCIS (ductal carcinoma in situ) formation. Helichrysetin possess strong inhibitory effects on cell growth and is capable of inducing apoptosis in A549 cells[1][2].

分子量

286.28

Formula

C16H14O5

CAS 号

62014-87-3

中文名称

蜡菊亭; 4,2′,4′-三羟基-6′-甲氧基查耳酮

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Liu Y, et al. ID2 and GJB2 promote early-stage breast cancer progression by regulating cancer stemness. Breast Cancer Res Treat. 2019 May;175(1):77-90.

    [2]. Ho YF, et al. Induction of apoptosis and cell cycle blockade by helichrysetin in a549 human lung adenocarcinoma cells. Evid Based Complement Alternat Med. 2013;2013:857257.

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