AM-Imidazole-PA-Boc

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AM-Imidazole-PA-Boc 

AM-Imidazole-PA-Boc 是一种 PROTAC linker，属于 alkyl chain 类。AM-Imidazole-PA-Boc 可用于合成 PROTAC IRAK4 degrader-1 (HY-129966)。

AM-Imidazole-PA-Boc

AM-Imidazole-PA-Boc Chemical Structure

CAS No. : 2357108-99-5

规格 价格 是否有货 数量
50 mg ￥15500 In-stock
100 mg   询价  
200 mg   询价  

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生物活性

AM-Imidazole-PA-Boc is an alkyl chain-based PROTAC linker can be used in the synthesis of PROTAC IRAK4 degrader-1 (HY-129966)[1].

IC50 & Target

Alkyl-Chain

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

254.33

Formula

C12H22N4O2
CAS 号

2357108-99-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
参考文献

  • [1]. Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.

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