13-Methylberberine chloride(Synonyms: 13-Methylberberinium chloride)

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13-Methylberberine chloride (Synonyms: 13-Methylberberinium chloride) 纯度: 99.16%

13-Methylberberine chloride (13-Methylberberinium chloride)，黄连素类似物，具有抗脂肪和抗肿瘤活性。13-Methylberberine chloride (13-Methylberberinium chloride) 可增加 IL-12 的产生，并在 LPS 激活的巨噬细胞转录后抑制 iNOS 的表达。

13-Methylberberine chloride(Synonyms: 13-Methylberberinium chloride)

13-Methylberberine chloride Chemical Structure

CAS No. : 54260-72-9

规格 价格 是否有货 数量
5 mg ￥4030 In-stock
10 mg ￥6860 In-stock
50 mg   询价  
100 mg   询价  

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13-Methylberberine chloride 相关产品

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生物活性

13-Methylberberine chloride (13-Methylberberinium chloride), a berberine analogue, has anti-adipogenic and antitumor activities. 13-Methylberberine chloride (13-Methylberberinium chloride) increases production of IL-12 and inhibits the expression of iNOS at posttranscriptional level in macrophages activated with LPS[1][2][3].

分子量

385.84

Formula

C21H20ClNO4
CAS 号

54260-72-9
中文名称

13-甲基小檗碱
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
参考文献

  • [1]. Chow YL, et al. 13-Methylberberine, a berberine analogue with stronger anti-adipogenic effects on mouse 3T3-L1 cells. Sci Rep. 2016 Dec 5;6:38129.

    [2]. Iwasa K, et al. In vitro cytotoxicity of the protoberberine-type alkaloids. J Nat Prod. 2001 Jul;64(7):896-8.

    [3]. Lee DU, et al. Effects of 13-alkyl-substituted berberine alkaloids on the expression of COX-II, TNF-alpha, iNOS, and IL-12 production in LPS-stimulated macrophages. Life Sci. 2003 Aug 1;73(11):1401-12.

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