Cyclo(RGDyK)

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Cyclo(RGDyK) 

Cyclo(RGDyK) 是一种有效的选择性 αVβ3 整联蛋白 (integrin) 抑制剂，IC50 为 20 nM。

Cyclo(RGDyK)

Cyclo(RGDyK) Chemical Structure

CAS No. : 217099-14-4

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Cyclo(RGDyK) 的其他形式现货产品:

Cyclo(RGDyK) trifluoroacetate

生物活性

Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM.

IC50 & Target

IC50: 20 nM (αVβ3 Integrin), 3000 nM (αIIbβ3 Integrin), 4000 nM (αVβ5 Integrin)[1]
体外研究
(In Vitro)

Cyclo(RGDyK) (c(RGDyK(SAA)) shows high affinity and selectivity for αVβ3 over αVβ5 (IC50=4000 nM) and αIIbβ3 (IC50=3000 nM)[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

619.67

Formula

C27H41N9O8
CAS 号

217099-14-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Haubner R, et al. Glycosylated RGD-containing peptides: tracer for tumor targeting and angiogenesis imaging with improved biokinetics. J Nucl Med. 2001 Feb;42(2):326-36.

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