Acetamide-15N(Synonyms: 乙酰胺 15N)

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Acetamide-15N (Synonyms: 乙酰胺 15N)

Acetamide-15N 是 15N 标记的 Acetamide。Acetamide 是合成甲胺,硫代乙酰胺和杀虫剂中间体,也用作皮革,布料和涂料中的增塑剂。 Acetamide 具有致癌性。

Acetamide-15N(Synonyms: 乙酰胺 15N)

Acetamide-15N Chemical Structure

CAS No. : 1449-72-5

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生物活性

Acetamide-15N is the 15N-labeled Acetamide. Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

60.06

Formula

C2H515NO

CAS 号

1449-72-5

中文名称

乙酰胺 15N

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Acetamide. IARC Monogr Eval Carcinog Risks Hum. 1999;71 Pt 3:1211-21.

    [3]. Moore MM, et, al. The food contaminant acetamide is not an in vivo clastogen, aneugen, or mutagen in rodent hematopoietic tissue. Regul Toxicol Pharmacol. 2019 Nov;108:104451.

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