Nortriptyline-d3 hydrochloride(Synonyms: Desmethylamitriptyline-d3 hydrochloride; Desitriptilina-d3 hydrochloride)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Nortriptyline-d3 hydrochloride (Synonyms: Desmethylamitriptyline-d3 hydrochloride; Desitriptilina-d3 hydrochloride)

Nortriptyline-d3 (Desmethylamitriptyline-d3) hydrochloride 是 Nortriptyline hydrochloride 的氘代物。Nortriptyline hydrochloride (Desmethylamitriptyline hydrochloride) 是三环类抗抑郁药,是 Amitriptyline 的主要活性代谢物,用于缓解抑郁症状。

Nortriptyline-d3 hydrochloride(Synonyms: Desmethylamitriptyline-d3 hydrochloride; Desitriptilina-d3 hydrochloride)

Nortriptyline-d3 hydrochloride Chemical Structure

CAS No. : 203784-52-5

规格 是否有货
2.5 mg Check price and availability
1 mg Check price and availability
5 mg Check price and availability
10 mg Check price and availability

* Please select Quantity before adding items.

生物活性

Nortriptyline-d3 (Desmethylamitriptyline-d3) hydrochloride is the deuterium labeled Nortriptyline hydrochloride. Nortriptyline hydrochloride (Desmethylamitriptyline hydrochloride) is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and used to relieve the symptoms of depression[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

302.86

Formula

C19H19D3ClN

CAS 号

203784-52-5

中文名称

盐酸去甲替林 d3 (盐酸盐)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Dean L. Amitriptyline Therapy and CYP2D6 and CYP2C19 Genotype. Biotechnology Information (US); 2012-2017 Mar 23.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

发表回复