FAAH inhibitor 1(Synonyms: Benzothiazole analog 3)

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FAAH inhibitor 1 (Synonyms: Benzothiazole analog 3)

FAAH inhibitor 1 (Benzothiazole analog 3) 是脂肪酸酰胺水解酶 (FAAH) 抑制剂，IC50 为 18 nM。

FAAH inhibitor 1(Synonyms: Benzothiazole analog 3)

FAAH inhibitor 1 Chemical Structure

CAS No. : 326866-17-5

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生物活性

FAAH inhibitor 1 (Benzothiazole analog 3) is a potent fatty acid amide hydrolase (FAAH) inhibitor with an IC50 of 18±8 nM[1].

分子量

497.65

Formula

C24H23N3O3S3
CAS 号

326866-17-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Wang, Xueqing; Sarris, Katerina; Kage, Karen; et al. Synthesis and Evaluation of Benzothiazole-Based Analogues as Novel, Potent, and Selective Fatty Acid Amide Hydrolase Inhibitors. Journal of Medicinal Chemistry (2009), 52(1), 170-180.

    [2]. Meyers, Marvin J.; Long, Scott A.; Pelc, Matthew J.; et al. Discovery of novel spirocyclic inhibitors of fatty acid amide hydrolase (FAAH). Part 1: Identification of 7-azaspiro[3.5]nonane and 1-oxa-8-azaspiro[4.5]decane as lead scaffolds. Bioorganic & Medicinal Chemistry Letters (2011), 21(21), 6538-6544.

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