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Alemtuzumab (Synonyms: Campath-IH; Lemtrada; MabCampath)
Alemtuzumab (Campath-IH) 是一种抗 CD52 的人源化单克隆抗体,CD52 是一种糖蛋白,在大多数淋巴细胞表面表达,在较小程度上也表达于髓细胞类型。阿仑单抗选择性靶向 CD52 抗原,诱导淋巴细胞深度耗竭,然后恢复具有调节表型的 T 细胞和 B 细胞。
Alemtuzumab Chemical Structure
CAS No. : 216503-57-0
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生物活性 |
Alemtuzumab (Campath-IH) is a humanized monoclonal antibody against CD52, a glycoprotein expressed on the surface of most lymphoid, and to a lesser extent, myeloid cell types. Alemtuzumab selectively targets the CD52 antigen to induce profound lymphocyte depletion, followed by recovery of T and B cells with regulatory phenotypes[1][2]. |
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CAS 号 |
216503-57-0 |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |
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