HDP 30.1699

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HDP 30.1699 

HDP 30.1699 是 α-鹅膏菌素衍生物,具有交联特性。抗 HER2 THIOMAB 抗体的半胱氨酸残基可用于连接半胱氨酸连接子和 HDP 30.1699。

HDP 30.1699

HDP 30.1699 Chemical Structure

CAS No. : 2004724-36-9

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生物活性

HDP 30.1699, the derivative of α-Amanitin,shows considerable cross-links. The cysteine residues of the anti-HER2 THIOMAB antibody are used for conjugation of the cysteine reactive linker–Amanitin compound, HDP 30.1699, with a cleavable linker by maleimide chemistry[1][2].

分子量

1345.44

Formula

C61H80N14O19S

CAS 号

2004724-36-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Torsten HECHLER, et al. Amanitin antibody conjugates. WO2018115466A1.

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