TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride

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TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride 

TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) 是抗体-药物偶联物的一部分,由 TLR7/8 激活剂 TLR7/8 agonist 4 (HY-139018) 和可降解的 ADC linker hydroxy-PEG10-acid (HY-133307) 连接而成。

TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride

TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride Chemical Structure

CAS No. : 2388520-36-1

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生物活性

TLR7/8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) is a drug-linker conjugate for ADC with potent antitumor activity by using TLR7/8 agonist 4 (HY-139018; a TLR7/8 agonist), linked via the cleavable ADC linker hydroxy-PEG10-acid (HY-133307)[1].

IC50 & Target[1]

Traditional Cytotoxic Agents

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

873.47

Formula

C41H69ClN6O12

CAS 号

2388520-36-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Shelley Erin ACKERMAN, et al. Immunoconjugates targeting her2. WO2020190725A1.

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