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(S,R,S)-AHPC-Me-C10-NH2
(S,R,S)-AHPC-Me-C5-COOH 是一种合成的 E3 连接酶配体结合物,它结合了 VHL 配体和 linker。(S,R,S)-AHPC-Me-C5-COOH 可用于 PROTAC MS432 (HY-130602)。
(S,R,S)-AHPC-Me-C10-NH2 Chemical Structure
CAS No. : 2376139-52-3
规格 | 价格 | 是否有货 | |
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50 mg | ¥9600 | 询问价格 & 货期 |
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生物活性 |
(S,R,S)-AHPC-Me-C10-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C10-NH2 can be used in PROTAC MS432 (HY-130602)[1]. |
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IC50 & Target[1] |
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体外研究 (In Vitro) |
MS432 is a first-in-class and highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
627.88 |
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Formula |
C34H53N5O4S |
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CAS 号 |
2376139-52-3 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
-20°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen) |
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参考文献 |
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