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IDO/TDO-IN-1
IDO/TDO-IN-1 (compound 25) 是一种高效的、具有口服活性的吲哚胺-2,3-双加氧酶 (IDO) 和色氨酸 2,3-双加氧酶 (TDO) 双重抑制剂，IC50 值分别为 9.7 nM 和 47 nM。
IDO/TDO-IN-1 Chemical Structure
CAS No. : 2033173-01-0
| 规格 | 是否有货 | ||
|---|---|---|---|
| 100 mg | 询价 | ||
| 250 mg | 询价 | ||
| 500 mg | 询价 |
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| 生物活性 |
IDO/TDO-IN-1 (compound 25) is a highly potent and orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor with IC50s of 9.7 and 47 nM, respectively [1]. |
IC50 & Target |
IC50: 9.7 nM (Indoleamine-2,3-dioxygenase), 47 nM (Tryptophan 2,3-dioxygenase)[1] |
|---|---|
| 体外研究 (In Vitro) |
IDO/TDO-IN-1 inhibits IDO in the Hela cell line with an IC50 of 76 nM[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
| 分子量 |
413.49 |
| Formula |
C25H24FN5 |
| CAS 号 |
2033173-01-0 |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 参考文献 |
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